Versatile reactivity of Pd-catalysts: features of the mono-N-protected AA ligand and cesium-X base in Pd-catalyzed C–H functionalization

Djamaladdin G. Musaev, Travis M. Figg and Alexey L. Kaledin

Chem. Soc. Rev.,
2014, 43, 5009-5031; 10.1039/C3CS60447K


The Musaev group have been probing the mechanistic details of the Pd-catalyzed C–H Functionalization and this review provides some of the highlights of their recent findings.

This overview explores some of the key features and questions involved in Pd-catalyzed C–H Functionalization, including the nature of the active species, the role of the amino-acid ligands around the Pd and the role and crucial nature of the base employed.

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