04/2014

The Yu group have recently reported some ground-breaking chemistry that significantly expands the scope of directed C–H Functionalization.

C–H Functionalization techniques that employ directing groups to select between C–H bonds typically result in the transformation of adjacent C–H bonds, those within 5-6 bonds distance. The design, synthesis and understanding of new templates guide the site of reaction to more distant C–H bonds, providing transformations at bonds upto 11 bonds away.