Cu(OAc)2-Catalyzed Coupling of Aromatic C–H Bonds with Arylboron Reagents

Ming Shang, Shang-Zheng Sun, Hui-Xiong Dai, and Jin-Quan Yu

Organic Letters,
2014, 16, (21), 5666-5669; 10.1021/ol5027377


The Yu Group report their latest advance in investigating copper-catalyzed directed C–H Functionalization.

By employing a readily removable directing group an arylboron reagents are introduced in a direct fashion providing a streamlined entry to biaryl compounds, chemical motifs of significant pharmaceutical interest.

This work adds to the ongoing program in the Yu group exploring copper-catalyzed C–H Functionalization.

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